Masaharu Hazawa Selected Research

Nuclear Pore Complex Proteins (Nucleoporins)

1/2022	Discovery of a Novel Aminocyclopropenone Compound That Inhibits BRD4-Driven Nucleoporin NUP210 Expression and Attenuates Colorectal Cancer Growth.
1/2021	Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma.
1/2017	High-Speed Atomic Force Microscopy Reveals Loss of Nuclear Pore Resilience as a Dying Code in Colorectal Cancer Cells.

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Masaharu Hazawa Research Topics

Disease

17	Neoplasms (Cancer) 01/2022 - 04/2009
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 01/2012
3	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 03/2018
2	Squamous Cell Carcinoma of Head and Neck 04/2020 - 01/2020
2	Human Influenza (Influenza) 01/2020 - 01/2020
2	Leukemia 11/2017 - 04/2011
2	Glioma (Gliomas) 05/2015 - 12/2007
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/2012 - 10/2011
1	Ependymoma 01/2021
1	Esophageal Squamous Cell Carcinoma 10/2020
1	Colonic Neoplasms (Colon Cancer) 10/2020
1	Rupture 01/2020
1	Adenoma (Adenomas) 01/2020
1	Influenza in Birds (Avian Flu) 01/2020
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018
1	Carcinogenesis 01/2018
1	Multiple Organ Failure (MODS) 12/2016
1	Parkinsonian Disorders (Parkinsonism) 05/2015
1	Measles 07/2014
1	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2013
1	Radiation Injuries (Radiation Sickness) 01/2012
1	Polyploidy 01/2012
1	Lymphoid Leukemia 04/2011
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 02/2011
1	Carcinoma (Carcinomatosis) 01/2011

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2012
5	AlkaloidsIBA 08/2012 - 12/2007
3	Nuclear Pore Complex Proteins (Nucleoporins)IBA 01/2022 - 01/2017
3	Biological ProductsIBA 01/2022 - 04/2011
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2021
2	Phosphotransferases (Kinase)IBA 01/2021 - 01/2018
2	Hemagglutinins (Hemagglutinin)IBA 01/2020 - 01/2020
2	Virulence Factors (Pathogenicity Factors)IBA 01/2020 - 01/2020
2	DiterpenesIBA 08/2012 - 01/2011
1	Pharmaceutical PreparationsIBA 01/2022
1	Beclin-1IBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	Mitogen-Activated Protein KinasesIBA 01/2021
1	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)IBA 01/2021
1	Bovine Serum AlbuminIBA 01/2021
1	Lamin Type B (Lamin B)IBA 01/2021
1	Chloroquine (Aralen)FDA LinkGeneric 01/2021
1	ChromatinIBA 01/2021
1	Mitogen-Activated Protein Kinase 8IBA 01/2021
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021
1	Phosphates (Orthophosphate)IBA 01/2021
1	Heat Shock Transcription FactorsIBA 01/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2021
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2021
1	Qa-SNARE Proteins (Syntaxin)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Autophagy-Related Protein-1 HomologIBA 01/2021
1	ARV-771IBA 10/2020
1	1,2-cyclohexanediolIBA 10/2020
1	romidepsin (FK228)FDA Link 10/2020
1	importazoleIBA 04/2020
1	B7-H1 AntigenIBA 04/2020
1	3- (4- methylphenylsulfonyl)- 2- propenenitrileIBA 01/2020
1	Karyopherins (Importin)IBA 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020
1	trametinibIBA 01/2020
1	Interleukin-23 (Interleukin 23)IBA 01/2020
1	BuffersIBA 01/2020
1	Glycogen Synthase KinasesIBA 03/2018
1	Glycogen Synthase (Synthase I)IBA 03/2018
1	Dyneins (Dynein)IBA 03/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2018
1	Sirtuin 2IBA 01/2018
1	Sirtuin 3IBA 01/2018
1	Ataxia Telangiectasia Mutated ProteinsIBA 01/2018
1	MLN 8237IBA 01/2017
1	Plasminogen Activators (Plasminogen Activator)IBA 12/2016
1	CateninsIBA 05/2015
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 05/2015
1	AntibodiesIBA 07/2014
1	Keratan SulfateIBA 01/2013
1	Proteoglycans (Proteoglycan)IBA 01/2013
1	CaspasesIBA 06/2012
1	homoserine lactoneIBA 02/2012
1	Radiation-Sensitizing AgentsIBA 01/2012
1	VitronectinIBA 01/2012
1	Acyl-ButyrolactonesIBA 01/2012
1	pyrazolanthroneIBA 01/2012
1	JNK Mitogen-Activated Protein KinasesIBA 01/2012
1	AcridinesIBA 01/2012
1	Hydroxyl RadicalIBA 08/2011
1	Laminin ReceptorsIBA 04/2011

Therapy/Procedure

1	Therapeutics 01/2021
1	Injections 10/2020